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Bill Gates surprised even his closest advisers when he said his dream is to eliminate the world's top 20 diseases in his lifetime. Gates-watchers say it's not naïve over-reaching. The Gateses have an optimistic belief in technology and management that, combined with their resources, could make a difference.

In the advertising world of Madison Avenue, three-martini lunches and chain smoking in the office are long gone. But women and minorities are still struggling to make inroads at the top agencies.

New York Gov. Kathy Hochul and other top officials weighed the political future of New York City's embattled Mayor Eric Adams. Adams faces growing calls to step down over allegations of corruption

The Washington Post newsroom is in an uproar as more red flags are revealed about how their new CEO, and the top editor he's hired got big scoops back in Britain.

NPR's Eric Weiner reports that Japan's worst economic downturn since World War II has radically changed expectations of young college graduates. In years past, the country's corporate giants would go to the top schools and actively recruit new employees, who generally were given jobs for life. Now it is the students who are chasing employers. And many of them are not finding jobs. Some have given up on full-time employment and simply bounce from one part-time job to another while living with their parents.

Southern California Edison, one of California's cash-strapped electric utilities, defaulted to some of its creditors today. It failed to repay, at least temporarily, a 596-million-dollar wholesale electricity bill. The move brings the company a step closer to bankruptcy. The utility said the action was necessary to allow it to continue operations while state and federal officials seek a regulatory solution to California's power crisis. The state, meanwhile, declared another top level power emergency today, citing a shortage of natural gas needed to generate electricity. Scott Horsley reports.

Noah Adams talks with reporter Tom Gibb about a massive fire which has crippled an enormous 40-story offshore oil rig located 75-miles off Brazil's Atlantic coast. Officials are trying to prevent a spill of the 400,000 gallons of oil on board. The rig may sink within 48 hours. Three explosions on Thursday damaged a pillar supporting the rig; the explosions killed one worker and left nine others missing and presumed dead. The offshore rig was Brazil's top oil producer in the rich Campos Basin.

Paul Bremer, the new U.S. civilian administrator for Iraq, arrives in Bagdhad as part of a broad shake-up in the U.S. reconstruction team. Moving out of the country are four top U.S. administrators amid charges that the team has been too slow restoring basic services and has failed to ensure security. NPR's Guy Raz reports.

Thomas Ricks, senior Pentagon correspondent for The Washington Post, discusses this week's long-awaited progress report from Gen. David Petraeus and Ambassador Ryan Crocker, the top two American officials in Iraq.

You can buy "full destroyed" high top sneakers. The sneakers come shredded and dirty. For a mere $1,850, you too, can look like you don't care how you look.