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The 4-decades long effort to create an AIDS vaccine suffered a blow with news that a vaccine in a late stage trial was discontinued because results showed it to be ineffective. What are the obstacles?

Large chains like Panera and P.F. Chang's as well as neighborhood hangouts are increasingly experimenting with the subscription model as a way to ensure steady revenue and customer visits.

Neither candidate was above the 50% threshold needed to win outright under Georgia law. This sets up a post-Thanksgiving showdown in what is already the country's most expensive Senate race.

The 50th anniversary of the Roe V. Wade decision is Jan. 22. NPR's podcast Throughline examines the debate about abortion, which wasn't always controversial. (Story aired on ATC on June 6, 2022.)

Rescuers have been racing to find survivors at an apartment complex attacked by Russian forces on Saturday. At least 40 people were killed, and more than 25 others are missing and feared dead.

President Biden is using his budget to show how he could cut the deficit and still fund his pledges like universal preschool, paid leave and more childcare funding.

Researchers used data from more than 150 countries to connect gender equality and life expectancy. They hope their findings can help policymakers set priorities in public health and other areas.

Polls, races to watch and vote counting: here's what to expect in the 2022 midterm elections.

Conspiracy theory provocateur Alex Jones has been ordered to pay nearly a billion dollars to the families of Sandy Hook Elementary School shooting victims. But will they ever see that money?

German authorities say they expect more arrests as they investigate an alleged plot to overthrow the government that led to dozens of arrests Wednesday across the country.