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More lockdowns are in the offing, as Germany and Austria shatter daily case counts and Russia has become become the world leader in new COVID-19 deaths.

There was enough working against Democrats inside and outside of New Jersey for the powerful state Senate president to lose his seat to a truck driver with no political experience.

South Dakota and Vermont are both small, rural states with Republican governors. They've taken very different approaches to coronavirus. One state has suffered far more illness and death.

Three inmates died in Mississippi state prisons this week, leading the governor to announce operational changes. On Friday, activists are rallying at the state capitol to demand prison reform.

Hurricane Delta, a 'major' category 3 storm, is expected to make landfall Friday evening in the same area Laura hit in August. Forecasters warn of a life-threatening storm surge and powerful winds.

Officials have known for years that Benton Harbor, Mich., has high levels of lead in the water. Now, Gov. Gretchen Whitmer has set an 18-month goal for replacing the lead pipes throughout the city.

Pfizer is seeking the FDA's permission to offer a third COVID-19 vaccine dose to those 16 and older. There's data that the vaccine's efficacy is waning and evidence that a booster can reverse that.

There are fresh logistical challenges, warns the White House's COVID czar in an exclusive interview with NPR. For example, young children will be getting a smaller dose delivered via smaller needles.

Fatalities have been reported after an explosion at an Ariana Grande concert in Manchester, England. 'Everyone just fled," says one concertgoer. "People were just running all over the place."

Ahead of the holidays, coronavirus cases are down, but the U.S. remains stuck in a cycle of regional outbreaks, even in heavily vaccinated northern states. Can boosters and kids vaccines make a dent?